Mariko Anzai
Mariko sick in bed while hospitalized
14 (during events of novel)
Alive (novel)
Deceased (if she is Mariko Brea in the video games)
Hair color
Eye color
Student (during novel)
Parasite Eve
Ayako Omura
I'm not Frankenstein's monster! I don't want to become a monster!

Mariko Anzai (安斉 麻理子 Anzai Mariko) is a character in the Parasite Eve novel. She is portrayed by Ayako Omura in the film adaptation.

In the video game continuity, it is likely she was adapted into the character Mariko Brea, who is the mother of Aya Brea and Maya Brea.

Parasite Eve (novel)

Mariko was a 14 year old girl who needed to have a kidney transplant due to an illness. She first received one when she was 12, but stopped taking her medicine as other students called her "a monster" and bullied her as she had someone else's organ; this made her body reject the kidney, having to remove it due to infection.

Mariko 2

Mariko senses Eve's presence.

After Kiyomi Nagashima became brain dead and died, Mariko was the candidate to receive Kiyomi's kidney. With the assistance of Takashi Yoshizumi, the operation was a success, but Mariko later complained about feeling weird and "hot", due to Kiyomi's advanced mitochondria now dwelling in her. Mariko then became the candidate to birth the Ultimate Being so the mitochondria began to change her uterus in order for her body to become compatible. This caused Mariko to start to have mini panic attacks, usually shouting and screaming out "it called to me, it's inside my stomach". Her doctor would later connect this to Kiyomi and to Toshiaki Nagashima's research.

Mariko survives at the end of the book.

Mariko Brea


Aya finding her mother's name in St. Francis Hospital.

It is mentioned in the Parasite Eve video games that the mother of Aya Brea and Maya Brea was named Mariko Brea. Since the timeline does not align perfectly for the Brea sisters' mother to have been Mariko Anzai (given the novel's contemporary setting), Mariko Brea is likely the video game incarnation of the novel character and they probably share the same backstories (minus the dates of events). This would explain Aya's and Maya's advanced mitochondria.

In the video game continuity, Mariko Brea moved to America, apparently living around the New York City and Boston area at various points in time. With a male Caucasian journalist who is presumably blonde, Mariko gave birth to two girls named Aya and Maya.

Mariko died with a cardiac arrest in the St. Francis Hospital in New York City along with Maya after a car accident on December 23, 1977. Like Kiyomi, it is possible that her death wasn't a freak accident; Mariko may have succumbed to the neo-mitochondria (possibly an incarnation of Eve) within her body.

Before her death, Mariko made herself and Maya organ donors (possibly due to Mariko being controlled by Eve). According to Kunihiko Maeda, Mariko's organs couldn't be transplanted after the accident. The reason isn't specified, although it is possible Mariko's body was too injured in the accident.

Differences between film and novel

In the novel, Mariko is "raped" by Eve and gives birth to the Ultimate Being, which is later destroyed. But in the film Mariko never gave birth, as this was thought to be "too disturbing" to put on film and was cut out. Instead, Eve simply began to prepare her for the birth; however, before that could be accomplished, both Kiyomi/Eve and Toshiaki commit a lover's suicide and Mariko was spared from giving birth. Mariko survives in both versions.